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[기본] Science Immunology Notification for 28 June 2024
사단법인과학키움
2024.06.30 07:17
조회 3
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Podcasts
VOLUME 9 | ISSUE 96 | 28 JUN 2024
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Science
Immunology on
Twitter
. We tweet regularly about our newest articles and share items of broad interest to the global community of immunologists.
FOCUS
|
INNATE IMMUNITY
Waking the sleeping giant: Single-stranded DNA binds Schlafen 11 to initiate innate immune responses
BY STEPHANIE A. RAGLAND, JONATHAN C. KAGAN
Single-stranded DNA containing CGT/A motifs binds to the helicase domain of Schlafen 11 (SLFN11) to initiate cell death and cytokine production via SLFN11 ribonuclease activity (see related Research Article by Zhang
et al.
).
READ MORE
RESEARCH ARTICLE
|
T CELLS
Targeting T cell plasticity in kidney and gut inflammation by pooled single-cell CRISPR screening
BY LEON U. B. ENK, MALTE HELLMIG,
ET AL.
A single-cell in vivo CRISPR screen highlights genes driving T cell tissue adaptation and plasticity in autoimmunity.
READ MORE
RESEARCH ARTICLE
|
CANCER IMMUNOLOGY
Overexpression of
Malat1
drives metastasis through inflammatory reprogramming of the tumor microenvironment
BY ELENA MARTINEZ-TERROBA, LEAH M. PLASEK-HEGDE,
ET AL.
Malat1
-overexpressing tumors secrete Ccl2 to promote macrophage recruitment and lung adenocarcinoma progression.
READ MORE
RESEARCH ARTICLE
|
INFLAMMATORY BOWEL DISEASE
MAIT cells monitor intestinal dysbiosis and contribute to host protection during colitis
BY YARA EL MORR, MARIELA FÜRSTENHEIM,
ET AL.
Beneficial interactions occur between MAIT cells and the microbiota during intestinal inflammation.
READ MORE
RESEARCH ARTICLE
|
T CELLS
Single-cell topographical profiling of the immune synapse reveals a biomechanical signature of cytotoxicity
BY MIGUEL DE JESUS, ALEXANDER H. SETTLE,
ET AL.
Cytotoxic T cells form topographically complex, undulatory immune synapses with their targets to promote killing.
READ MORE
RESEARCH ARTICLE
|
INNATE IMMUNITY
Schlafen 11 triggers innate immune responses through its ribonuclease activity upon detection of single-stranded DNA
BY PENG ZHANG, XIAOQING HU,
ET AL.
Recognition of intracellular ssDNA containing CGT motifs by Schlafen 11 activates cytokine expression and cell death.
READ MORE
RESEARCH ARTICLE
|
T CELLS
Circulating KLRG1
+
long-lived effector memory T cells retain the flexibility to become tissue resident
BY ERIN D. LUCAS, MATTHEW A. HUGGINS,
ET AL.
Circulating KLRG1
+
memory T cells rapidly enter nonlymphoid tissues after viral infection and differentiate into resident memory.
READ MORE
RESEARCH ARTICLE
|
CORONAVIRUS
SARS-CoV-2 inflammation durably imprints memory CD4 T cells
BY SOPHIE L. GRAY-GAILLARD, SABRINA M. SOLIS,
ET AL.
High-grade inflammation due to SARS-CoV-2 infection imparts a durable transcriptional and epigenetic imprint on memory CD4 T cells.
READ MORE
RESEARCH ARTICLE
|
NK CELLS
Cytokines drive the formation of memory-like NK cell subsets via epigenetic rewiring and transcriptional regulation
BY JENNIFER A. FOLTZ, JENNIFER TRAN,
ET AL.
IL-12/15/18 differentially activate cNK cell subsets driving unique memory-like programs with implications for NK cell therapy.
목록
다음글 |
Science Advances Notification for 28 June 2024
이전글 |
Biomolecules, Volume 14, Issue 6 (June 2024) Table of Contents