| Please click here to view this in your browser. | | |  | | | |  | | | Millions of people around the world are diagnosed with cancer each year. The rapid proliferation of mutated cells can fatally risk health and well-being. Since President Richard Nixon declared the ‘war on cancer’ in 1971, billions of dollars have gone toward cancer research and how to better treat it ... |
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| | |  | | | Cancer is a disease in which mutated cells grow rapidly and uncontrollably. Unfortunately, these cells resist the body’s immune response and override immune response mechanisms to progress. Cancer is characterized by many different features, including chronic inflammation, which polarizes healthy immune ... |
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| | |  | | | Thinking of having a midnight snack? Think again. That midnight snack you crave can contribute to an increased risk of obesity, and an increase in body fat, keeping one from successfully losing weight. Nearly half of the U.S. adult population is considered obese. Obesity can result in chronic diseases such as cancer, diabetes, and other health-related problems ... |
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| | | | | Dr. Vijay Kuchroo - Director, The Gene Lay Institute of Immunology and Inflammation</br> Brigham and Women's Hospital, Harvard Medical School Expression of co-inhibitory receptors or “checkpoint” molecules, such as CTLA-4 and PD-1, on effector T cells is a key mechanism for ensuring immune homeostasis. Dysregulated expression of co-inhibitory receptors on CD4+ T cells promotes autoimmunity while sustained overexpression on CD8+ T cells promotes T cell dysfunction or exhaustion, leading to impaired ability to clear chronic ... |
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