New articles from eLife

Neuroscience, Computational and Systems Biology

MorphoCellSorter: An Andrews plot-based sorting approach to rank microglia according to their morphological features

Sarah Benkeder, Son-Michel Dinh ... Jean-Christophe Comte

Microbiology and Infectious Disease

Tuberculosis susceptibility in genetically diverse mice reveals functional diversity of neutrophils

Mariëtta M Ravesloot-Chávez, Erik Van Dis ... Sarah A Stanley

Neuroscience

A conserved code for anatomy: Neurons throughout the brain embed robust signatures of their anatomical location into spike trains

Gemechu B Tolossa, Aidan M Schneider ... Keith B Hengen

Cell Biology

The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence

Fan Zhang, Yuan Wang ... Xianpeng Ge

Neuroscience

Stable sequential dynamics in prefrontal cortex represents subjective estimation of time

Yiting Li, Wenqu Yin ... Baoming Li

Neuroscience, Evolutionary Biology

Cellular evolution of the hypothalamic preoptic area of behaviorally divergent deer mice

Jenny Chen, Phoebe R Richardson ... Hopi E Hoekstra

Neuroscience

Value construction through sequential sampling explains serial dependencies in decision making

Ariel Zylberberg, Akram Bakkour ... Michael N Shadlen

Chromosomes and Gene Expression, Genetics and Genomics

A genome-wide nucleosome-resolution map of promoter-centered interactions in human cells corroborates the enhancer-promoter looping model

Arkadiy K Golov, Alexey A Gavrilov ... Sergey V Razin

Neuroscience

Discriminating neural ensemble patterns through dendritic computations in randomly connected feedforward networks

Bhanu Priya Somashekar, Upinder Singh Bhalla

Neuroscience

A spatial threshold for astrocyte calcium surge

Justin Lines, Andres Baraibar ... Alfonso Araque

Biochemistry and Chemical Biology, Structural Biology and Molecular Biophysics

A conformational fingerprint for amyloidogenic light chains

Cristina Paissoni, Sarita Puri ... Carlo Camilloni

Neuroscience

Interneuron FGF13 regulates seizure susceptibility via a sodium channel-independent mechanism

Susan Lin, Aravind R Gade ... Geoffrey S Pitt

Neuroscience

Multimodal mismatch responses in mouse auditory cortex

Magdalena Solyga, Georg B Keller

Neuroscience

The transformation of sensory to perceptual braille letter representations in the visually deprived brain

Marleen Haupt, Monika Graumann ... Radoslaw M Cichy

Ecology

Habitat fragmentation mediates the mechanisms underlying long-term climate-driven thermophilization in birds

Juan Liu, Morgan W Tingley ... Xingfeng Si

Microbiology and Infectious Disease

Paracrine rescue of MYR1-deficient Toxoplasma gondii mutants reveals limitations of pooled in vivo CRISPR screens

Francesca Torelli, Diogo M da Fonseca ... Moritz Treeck

Epidemiology and Global Health

Measuring changes in Plasmodium falciparum census population size in response to sequential malaria control interventions

Kathryn E Tiedje, Qi Zhan ... Karen P Day

Biochemistry and Chemical Biology

Identification of Suitable Target/E3 Ligase Pairs for PROTAC Development using a Rapamycin-induced Proximity Assay (RiPA)

Bikash Adhikari, Katharina Schneider ... Elmar Wolf

Immunology and Inflammation, Microbiology and Infectious Disease

The Shigella flexneri effector IpaH1.4 facilitates RNF213 degradation and protects cytosolic bacteria against interferon-induced ubiquitylation

Luz Saavedra-Sanchez, Mary S Dickinson ... Jörn Coers

Neuroscience

Complementary cognitive roles for D2-MSNs and D1-MSNs during interval timing

R Austin Bruce, Matthew A Weber ... Nandakumar S Narayanan

Neuroscience

Auditory Cortex Learns to Discriminate Audiovisual Cues through Selective Multisensory Enhancement

Song Chang, Beilin Zheng ... Liping Yu

Neuroscience

Unravelling the neurocognitive mechanisms underlying counterconditioning in humans

Lisa Wirz, Maxime C Houtekamer ... Erno J Hermans

Evolutionary Biology

Seasonal and comparative evidence of adaptive gene expression in mammalian brain size plasticity

William R Thomas, Troy Richter ... Liliana M Dávalos

Biochemistry and Chemical Biology, Structural Biology and Molecular Biophysics

Control of 3ʹ splice site selection by the yeast splicing factor Fyv6

Katherine A Senn, Karli A Lipinski ... Aaron A Hoskins

Stem Cells and Regenerative Medicine

Nicotine enhances the stemness and tumorigenicity in intestinal stem cells via Hippo-YAP/TAZ and Notch signal pathway

Ryosuke Isotani, Masaki Igarashi ... Toshimasa Yamauchi

Microbiology and Infectious Disease

Lacticaseibacillus rhamnosus P118 enhances host tolerance to Salmonella infection by promoting microbe-derived indole metabolites

Baikui Wang, Xianqi Peng ... Min Yue

Microbiology and Infectious Disease

Differences in HIV-1 reservoir size, landscape characteristics and decay dynamics in acute and chronic treated HIV-1 Clade C infection

Kavidha Reddy, Guinevere Q Lee ... Thumbi Ndung’u

Epidemiology and Global Health

Lifestyles and their relative contribution to biological aging across multiple organ systems: change analysis from the China Multi-Ethnic Cohort Study

Yuan Zhang, Dan Tang ... Xing Zhao

Structural Biology and Molecular Biophysics, Plant Biology

Molecular dynamics simulations illuminate the role of sequence context in the ELF3-PrD-based temperature sensing mechanism in plants

Richard J Lindsay, Rafael Giordano Viegas ... Sonya M Hanson

Cell Biology, Genetics and Genomics

Multi-species genome-wide CRISPR screens identify conserved suppressors of cold-induced cell death

Breanna Lam, Kathrin M Kajderowicz ... Sinisa Hrvatin

Developmental Biology

Mesenchymal Meis2 controls whisker development independently from trigeminal sensory innervation

Mehmet Mahsum Kaplan, Erika Hudacova ... Ondrej Machon

Neuroscience

Proactive distractor suppression in early visual cortex

David Richter, Dirk van Moorselaar, Jan Theeuwes

Neuroscience

An antisense oligonucleotide-based strategy to ameliorate cognitive dysfunction in the 22q11.2 Deletion Syndrome

Pratibha Thakur, Martin Lackinger ... Joseph A Gogos

Neuroscience

Homeostatic synaptic normalization optimizes learning in network models of neural population codes

Jonathan Mayzel, Elad Schneidman

Medicine

Early menarche and childbirth accelerate aging-related outcomes and age-related diseases: Evidence for antagonistic pleiotropy in humans

Yifan Xiang, Vineeta Tanwar ... Pankaj Kapahi

Genetics and Genomics, Medicine

Single-cell characterization of menstrual fluid at homeostasis and in endometriosis

Petra C Schwalie, Cemsel Bafligil ... Angela Goncalves

Cancer Biology

Unveiling chemotherapy-induced immune landscape remodeling and metabolic reprogramming in lung adenocarcinoma by scRNA-sequencing

Yiwei Huang, Gujie Wu ... Cheng Zhan

Biochemistry and Chemical Biology, Neuroscience

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