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[기본] Immunology News: Antibody Discovery Improves Malaria Treatment & more...

사단법인과학키움 2024.11.24 17:01 조회 1554
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Antibody Discovery Improves Malaria Treatment

Malaria is a life-threatening disease that is transferred by mosquito bites. Interestingly, a specific type of mosquito can carry the disease. The transfer of the parasite to humans travels to the liver where it can lie dormant for weeks before infecting red blood cells. Once the infection spreads to the blood ...
 

Thymus Established Earlier than Previously Thought

Our immune systems begin developing long before we are born. Immune cells are generated around 4-weeks after gestation and continue to grow while in utero. As a result, we are protected from infection and invading pathogen until we are born. Newborn infants are then exposed to new antigens and external stimuli in ...
 

Engineered Probiotics Deliver Immunotherapy to the Gut

You can find probiotics, live microorganisms that have health benefits when consumed, in fermented foods like yogurt, sauerkraut, and kombucha. In addition, dietary supplements containing probiotics can help regulate digestion and keep the gastrointestinal (GI) tract functioning optimally. Many probiotics are ...
 

Brain Cells Boost Damage Caused by Alzheimer's Risk Variant

Sometimes there are slightly different versions, or sequences of genes. There are several versions of the apolipoprotein E (APOE) gene, for example. One of them, called APOE4, has been linked to a much higher risk of developing Alzheimer's disease, and carriers often have worse forms of the disease compared to ...
 

Lack of Dietary Zinc Can Promote Acinetobacter Lung Infections

New research has shown that a lack of dietary zinc can boost the chances of a lung infection caused by Acinetobacter baumannii bacteria; these pathogens are a major reason why people on ventilators get sick with pneumonia. This study has found a connection between molecules that promote inflammation and A ...
 

A Genetic Deficiency That Raises Susceptibility to Many Types of Flu

There are many processes and proteins that help the body fight a flu infection. One of them is known as IFITM3. Researchers have now shown that this protein can help prevent viruses from mutating after they have infected a new host. But some people are deficient ...
 
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Expression of co-inhibitory receptors or “checkpoint” molecules, such as CTLA-4 and PD-1, on effector T cells is a key mechanism for ensuring immune homeostasis. Dysregulated expression of co-inhibitory receptors on CD4+ T cells promotes autoimmunity while sustained overexpression on CD8+ T cells promotes T cell dysfunction or exhaustion, leading to impaired ability to clear chronic ...

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