New articles from eLife

Ecology

Interactions between wild pigs and the spread of disease

Mercury Shitindo

Tracking wild pigs with GPS devices reveals how their social interactions could influence the spread of disease, offering new strategies for protecting agriculture, wildlife, and human health.

Computational and Systems Biology

Mapping mitochondrial aging

Alessandro Bitto

Measuring mitochondrial respiration in frozen tissue samples provides the first comprehensive atlas of how aging affects mitochondrial function in mice.

Neuroscience

Nutritional state-dependent modulation of Insulin-Producing Cells in Drosophila

Rituja S Bisen, Fathima Mukthar Iqbal ... Jan M Ache

Cell Biology, Neuroscience

Psychological stress disturbs bone metabolism via miR-335-3p/Fos signaling in osteoclast

Jiayao Zhang, Juan Li ... Weicai Liu

Cell Biology, Evolutionary Biology

Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25

P Richard J Yulo, Nicolas Desprat ... Heather L Hendrickson

Computational and Systems Biology, Physics of Living Systems

Overflow metabolism originates from growth optimization and cellheterogeneity

Xin Wang

Cell Biology

Defective Neurogenesis in Lowe Syndrome is Caused by Mitochondria Loss and Cilia-related Sonic Hedgehog Defects

Chien-Hui Lo, Siyu Chen ... Yang Sun

Cell Biology

Naa10 regulates hippocampal neurite outgrowth via Btbd3 N-α-acetylation-mediated actin dynamics

Chien-Te Chou, Ming-Lun Kang ... Li-Jung Juan

Neuroscience

Outer hair cells stir cochlear fluids

Choongheon Lee, Mohammad Shokrian ... Jong-Hoon Nam

Developmental Biology, Computational and Systems Biology

Dorsal/NF-κB exhibits a dorsal-to-ventral mobility gradient in the Drosophila embryo

Hadel Al Asafen, Natalie M Clark ... Gregory T Reeves

Cell Biology

A fat-2(wa17) suppressor screen in C. elegans reveals genetic adaptations to polyunsaturated fatty acid deficiency

Delaney Kaper, Uroš Radović ... Marc Pilon

Neuroscience

Inferring illness causes recruits the animacy semantic network

Miriam Hauptman, Marina Bedny

Neuroscience

Differential destinations, dynamics, and functions of high- and low-order features in the feedback signal during object processing

Wenhao Hou, Sheng He, Jiedong Zhang

Ecology

Combining radio-telemetry and radar measurements to test optimal foraging in an aerial insectivore bird

Itai Bloch, David Troupin ... Nir Sapir

Evolutionary Biology

Horizontally transferred cell-free chromatin particles function as autonomous “predatory” genomes and vehicles for transposable elements within host cells

Soumita Banerjee, Soniya Shende ... Indraneel Mittra

Cancer Biology

Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation

Trang H Pham, Kanika Bajaj Pahuja ... Anwesha Dey

Genetics and Genomics, Evolutionary Biology

The integrated WF-Haldane (WFH) model of genetic drift resolving the many paradoxes of molecular evolution

Yongsen Ruan, Xiaopei Wang ... Chung-I Wu

Cell Biology

Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis

Joan Chang, Adam Pickard ... Karl E Kadler

Cell Biology

Characterization of the cellular components of mouse collecting lymphatic vessels reveals that lymphatic muscle cells are the innate pacemaker cells regulating lymphatic contractions

Scott D Zawieja, Grace A Pea ... Michael J Davis

Immunology and Inflammation

Downregulation of Semaphorin 4A in keratinocytes reflects the features of non-lesional psoriasis

Miki Kume, Hanako Koguchi-Yoshioka ... Rei Watanabe

Cell Biology

Chemotherapy resistance due to epithelial-to-mesenchymal transition is caused by abnormal lipid metabolic balance

Atsushi Matsumoto, Akihito Inoko ... Junichi Ikenouchi

Computational and Systems Biology

MGPfact^XMBD: A Model-Based Factorization Method for scRNA Data Unveils Bifurcating Transcriptional Modules Underlying Cell Fate Determination

Jun Ren, Ying Zhou ... Qiyuan Li

Cell Biology, Neuroscience

The effects of 17α-estradiol treatment on endocrine system revealed by single-nucleus transcriptomic sequencing of hypothalamus

Lei Li, Guanghao Wu ... Yinchuan Li

Structural Biology and Molecular Biophysics

Mechanism of expanded DNA recognition in xCas9

Kazi A Hossain, Lukasz Nierzwicki ... Giulia Palermo

Neuroscience

Assessing the balance between excitation and inhibition in chronic pain through the aperiodic component of EEG

Cristina Gil Avila, Elisabeth S May ... Markus Ploner

Neuroscience

NeuroSCAN: Exploring Neurodevelopment via Spatiotemporal Collation of Anatomical Networks

Noelle L Koonce, Sarah E Emerson ... Daniel Colón-Ramos

Neuroscience

Tachykinin1-expressing neurons in the parasubthalamic nucleus control active avoidance learning

Ruining Hu, Nannan Wu ... Rongfeng K Hu

Biochemistry and Chemical Biology

Exploiting functional regions in the viral RNA genome as druggable entities

Dehua Luo, Yingge Zheng ... Dengguo Wei

Immunology and Inflammation

Gasdermin D-Mediated Neutrophil Pyroptosis drives Inflammation in Psoriasis

Jian Liu, YuYing Jiang ... ZhiQiang Yin

Neuroscience

Dissociable after-effects of prosocial acts: Effort is costly for others but valued for self

Ya Zheng, Rumeng Tang

Neuroscience

Mother-child dyadic interactions shape children’s social brain and theory of mind

Lei Li, Jinming Xiao ... Xujun Duan

Neuroscience

Three-dimensional single-cell transcriptome imaging of thick tissues

Rongxin Fang, Aaron R Halpern ... Xiaowei Zhuang

Biochemistry and Chemical Biology, Genetics and Genomics

High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery

Conor J Howard, Nathan S Abell ... Nathan B Lubock

Microbiology and Infectious Disease

Avian-specific Salmonella enterica Serovar Gallinarum transition to endemicity is accompanied by localized resistome and mobilome interaction

Chenghao Jia, Chenghu Huang ... Min Yue

Neuroscience

Bridging the 3D geometrical organisation of white matter pathways across anatomical length scales and species

Hans Martin Kjer, Mariam Andersson ... Tim B Dyrby

Cell Biology, Developmental Biology

Human formin FHOD3-mediated actin elongation is required for sarcomere integrity in cardiomyocytes

Dylan A Valencia, Angela N Koeberlein ... Margot E Quinlan

Developmental Biology

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